Concepedia

Discovery and engineering of enhanced SUMO protease enzymes

Yue-Ting K. Lau, Vladimir Baytshtok, Tessa Howard, Brooke Fiala, JayLee M. Johnson, Lauren Carter, David Baker, Christopher D. Lima, Christopher D. Bahl

Journal of Biological Chemistry · 2018 · 86 citations · 29 references

DOIFull text

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Concepts

Abstract

, we have obtained proteases that are more soluble, more thermostable, and more efficient than the current commercially available Ulp1 enzyme.

References

29

[20] Processing of X-ray diffraction data collected in oscillation mode

Zbyszek Otwinowski, W. Minor · Methods in enzymology on CD-ROM/Methods in enzymology · 1997 · 33.6K citations

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Features and development of <i>Coot</i>

Paul Emsley, Bernhard Lohkamp, W. G. Scott et al. · Acta Crystallographica Section D Biological Crystallography · 2010 · 29.6K citations · Full text

, , +16

<i>PHENIX</i>: a comprehensive Python-based system for macromolecular structure solution

Paul D. Adams, Pavel V. Afonine, G. Bunkóczi et al. · Acta Crystallographica Section D Biological Crystallography · 2010 · 24.5K citations · Full text

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<i>Phaser</i>crystallographic software

Airlie J. McCoy, Ralf W. Grosse‐Kunstleve, Paul D. Adams et al. · Journal of Applied Crystallography · 2007 · 20.9K citations · Full text

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Protein structure prediction and analysis using the Robetta server

David E. Kim, Dylan Chivian, David Baker · Nucleic Acids Research · 2004 · 2.2K citations · Full text

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