Prevention of <i>M. tuberculosis</i> Infection with H4:IC31 Vaccine or BCG Revaccination

Abstract

In this trial, the rate of sustained QFT conversion, which may reflect sustained M. tuberculosis infection, was reduced by vaccination in a high-transmission setting. This finding may inform clinical development of new vaccine candidates. (Funded by Aeras and others; C-040-404 ClinicalTrials.gov number, NCT02075203 .).