Sterilization of granulomas is common in active and latent tuberculosis despite within-host variability in bacterial killing

Philana Ling Lin, Christopher B. Ford, M. Teresa Coleman, +6

Nature Medicine

Medical MicrobiologyPulmonary TuberculosisLatent TuberculosisGranulocyteTuberculosis Prevention +9

Variability in Tuberculosis Granuloma T Cell Responses Exists, but a Balance of Pro- and Anti-inflammatory Cytokines Is Associated with Sterilization

Hannah P. Gideon, Jia Yao Phuah, Amy Myers, +10

PLoS Pathogens

InflammationPulmonary TuberculosisAdaptive Immune SystemT CellsGranulocyte +11

Early Changes by ¹⁸ Fluorodeoxyglucose Positron Emission Tomography Coregistered with Computed Tomography Predict Outcome after Mycobacterium tuberculosis Infection in Cynomolgus Macaques

M. Teresa Coleman, Pauline Maiello, Jaime Tomko, +5

Infection and Immunity

PET/CT imaging reveals a therapeutic response to oxazolidinones in macaques and humans with tuberculosis

M. Teresa Coleman, Ray Y. Chen, Myungsun Lee, +14

Science Translational Medicine

PET CT Identifies Reactivation Risk in Cynomolgus Macaques with Latent M. tuberculosis

Philana Ling Lin, Pauline Maiello, Hannah P. Gideon, +15

PLoS Pathogens

InflammationPulmonary TuberculosisInflammatory Lung DiseaseLung InflammationTnf Neutralization +13

Differential Virulence and Disease Progression following Mycobacterium tuberculosis Complex Infection of the Common Marmoset (Callithrix jacchus)

Laura E. Via, Daniel Schimel, Philana Ling Lin, +17

Infection and Immunity

Pathogenic MicrobiologyDisease ProgressionPathologyCommon MarmosetBacterial Pathogenesis +17

Effects of B Cell Depletion on Early Mycobacterium tuberculosis Infection in Cynomolgus Macaques

Jia Yao Phuah, Eileen A. Wong, Hannah P. Gideon, +8

Infection and Immunity

Humoral ResponseImmunologyImmunologic MechanismCynomolgus MacaquesNonhuman Primates +18

Analysis of <sup>18</sup>FDG PET/CT Imaging as a Tool for Studying <em>Mycobacterium tuberculosis</em> Infection and Treatment in Non-human Primates

Alexander G. White, Pauline Maiello, M. Teresa Coleman, +5

Journal of Visualized Experiments

Positron Emission Tomography Imaging of Macaques with Tuberculosis Identifies Temporal Changes in Granuloma Glucose Metabolism and Integrin α4β1–Expressing Immune Cells

Joshua T. Mattila, Wissam Beaino, Pauline Maiello, +5

The Journal of Immunology

Analysis of <sup>18</sup>FDG PET/CT Imaging as a Tool for Studying <em>Mycobacterium tuberculosis</em> Infection and Treatment in Non-human Primates

Alexander G. White, Pauline Maiello, M. Teresa Coleman, +5

Journal of Visualized Experiments

Oncologic ImagingPet-mriPathologyDiagnostic ImagingPositron Emission Tomography +17