Concepedia
Nature Chemistry · 2018 · 178 citations · 22 references
Open access
Life SciencesBiochemistryChemistryBiocatalysisCatalysisEnzymologyCatalytic MechanismsCatalytic Residue FunctionEnzyme CatalysisEnzyme-substrate RecognitionHydrate FormationCatalytic Residue ConservationCatalytic Residue DesignHydrazone FormationHydrazone LigationOxime Ligation
22
Computational Design of an Enzyme Catalyst for a Stereoselective Bimolecular Diels-Alder Reaction
Justin B. Siegel, Alexandre Zanghellini, Helena M. Lovick et al. · Science · 2010 · 927 citations
Engineering, Biochemistry, Chemistry +17
Nucleophilic Catalysis of Hydrazone Formation and Transimination: Implications for Dynamic Covalent Chemistry
Anouk Dirksen, Sjoerd Dirksen, Tilman M. Hackeng et al. · Journal of the American Chemical Society · 2006 · 432 citations
Natural Sciences, Chemistry, Catalysis +12
Generation of a Bacterium with a 21 Amino Acid Genetic Code
Ryan A. Mehl, J. Christopher Anderson, Stephen W. Santoro et al. · Journal of the American Chemical Society · 2003 · 286 citations
Life Sciences, Genetics, Microbiology +17
Control of the <i>exo</i> and <i>endo</i> Pathways of the Diels-Alder Reaction by Antibody Catalysis
Véronique Gouverneur, K. N. Houk, Beatriz de Pascual‐Teresa et al. · Science · 1993 · 215 citations
Pharmacy, Biochemistry, Chemistry +13
An antibody-catalyzed bimolecular Diels-Alder reaction
Andrew C. Braisted, Peter G. Schultz · Journal of the American Chemical Society · 1990 · 206 citations
Pharmacy, Biochemistry, Chemistry +6