Ryan A. Mehl

Generation of a Bacterium with a 21 Amino Acid Genetic Code

Ryan A. Mehl, J. Christopher Anderson, Stephen W. Santoro et al. · Journal of the American Chemical Society · 2003 · 280 citations

Engineering, Genetics, Bacteriology +17

Optimized orthogonal translation of unnatural amino acids enables spontaneous protein double-labelling and FRET

Kaihang Wang, Amit Sachdeva, Daniel J. Cox et al. · Nature Chemistry · 2014 · 269 citations · Full text

Protein Chemistry, Biochemistry, Protein Assembly +12

Conformationally strained trans-cyclooctene with improved stability and excellent reactivity in tetrazine ligation

Ampofo Darko, Stephen Wallace, Olga Dmitrenko et al. · Chemical Science · 2014 · 268 citations · Full text

Genetically Encoded Tetrazine Amino Acid Directs Rapid Site-Specific <i>in Vivo</i> Bioorthogonal Ligation with <i>trans</i>-Cyclooctenes

Jason L. Seitchik, Jennifer C. Peeler, Michael T. Taylor et al. · Journal of the American Chemical Society · 2012 · 264 citations · Full text

Engineering, Molecular Biology, Reaction Rates +18

ATRP under Biologically Relevant Conditions: Grafting from a Protein

Saadyah Averick, Antonina Simakova, Sangwoo Park et al. · ACS Macro Letters · 2011 · 248 citations