Justin B. Siegel

Computational Design of an Enzyme Catalyst for a Stereoselective Bimolecular Diels-Alder Reaction

Justin B. Siegel, Alexandre Zanghellini, Helena M. Lovick et al. · Science · 2010 · 917 citations

Bioorganic Chemistry, Engineering, Biochemistry +15

Computational protein design enables a novel one-carbon assimilation pathway

Justin B. Siegel, Amanda Lee Smith, Sean Poust et al. · Proceedings of the National Academy of Sciences · 2015 · 397 citations · Full text

One-carbon Formaldehyde Molecules, Engineering, Protein Assembly +18

Increased Diels-Alderase activity through backbone remodeling guided by Foldit players

Christopher B. Eiben, Justin B. Siegel, Jacob B. Bale et al. · Nature Biotechnology · 2012 · 315 citations · Full text

Cellular Enzymology, Protein Assembly, Biochemistry +10

Computational Design of an α-Gliadin Peptidase

Sydney Gordon, Elizabeth J. Stanley, Sarah Wolf et al. · Journal of the American Chemical Society · 2012 · 124 citations · Full text

Glycobiology, Molecular Biology, Celiac Disease +16

Impact of scaffold rigidity on the design and evolution of an artificial Diels-Alderase

Nathalie Preiswerk, Tobias Beck, Jessica D. Schulz et al. · Proceedings of the National Academy of Sciences · 2014 · 121 citations · Full text