A designer self-assembled supramolecule amplifies macrophage immune responses against aggressive cancer

CSF-1R inhibition alters macrophage polarization and blocks glioma progression

Stephanie M. Pyonteck, Leila Akkari, Alberto J. Schuhmacher et al. · Nature Medicine · 2013 · 2.4K citations · Full text

Neuro-oncology, Glioma, Medicine +8

Targeting Tumor-Associated Macrophages with Anti-CSF-1R Antibody Reveals a Strategy for Cancer Therapy

Carola H. Ries, Michael A. Cannarile, Sabine Hoves et al. · Cancer Cell · 2014 · 1.3K citations

Cancer Therapy, Tumor Biology, Tumor-associated Macrophages +12

M1 and M2 macrophages derived from THP-1 cells differentially modulate the response of cancer cells to etoposide

Marie Genin, C. François, Antoine Fattaccioli et al. · BMC Cancer · 2015 · 1.1K citations · Full text

Macrophage IL-10 Blocks CD8+ T Cell-Dependent Responses to Chemotherapy by Suppressing IL-12 Expression in Intratumoral Dendritic Cells

Brian Ruffell, Debbie Chang-Strachan, Vivien W. Chan et al. · Cancer Cell · 2014 · 967 citations · Full text

Inflammation, Cancer Immunosurveillance, Immunology +9

Disrupting the CD47-SIRPα anti-phagocytic axis by a humanized anti-CD47 antibody is an efficacious treatment for malignant pediatric brain tumors

Sharareh Gholamin, Siddhartha S. Mitra, Abdullah H. Feroze et al. · Science Translational Medicine · 2017 · 413 citations