Concepedia

Design, synthesis, in vitro and in vivo evaluation, and structure-activity relationship (SAR) discussion of novel dipeptidyl boronic acid proteasome inhibitors as orally available anti-cancer agents for the treatment of multiple myeloma and mechanism studies

Meng Lei, Huayun Feng, Enhe Bai, Hui Zhou, Jia Wang, Jingmiao Shi, Xueyuan Wang, Shihe Hu, Zhaogang Liu, Yongqiang Zhu

Bioorganic & Medicinal Chemistry · 2018 · 12 citations · 18 references

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References

18

A Phase 2 Study of Bortezomib in Relapsed, Refractory Myeloma

Paul G. Richardson, Bart Barlogie, James R. Berenson et al. · New England Journal of Medicine · 2003 · 2.6K citations · Full text

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Bortezomib or High-Dose Dexamethasone for Relapsed Multiple Myeloma

Paul G. Richardson, Pieter Sonneveld, Michael W. Schuster et al. · New England Journal of Medicine · 2005 · 2.5K citations · Full text

, , +14

Structure of 20S proteasome from yeast at 2.4Å resolution

M. Groll, Lars Ditzel, Jan Löwe et al. · Nature · 1997 · 2.3K citations

, , +10

Multicenter Phase II Study of Bortezomib in Patients With Relapsed or Refractory Mantle Cell Lymphoma

Richard I. Fisher, Steven H. Bernstein, Brad S. Kahl et al. · Journal of Clinical Oncology · 2006 · 708 citations

, , +15

Complete subunit architecture of the proteasome regulatory particle

Gabriel C. Lander, Eric Estrin, Mary E. Matyskiela et al. · Nature · 2012 · 619 citations

, , +12