Huayun Feng

Design, synthesis, SAR discussion, in vitro and in vivo evaluation of novel selective EGFR modulator to inhibit L858R/T790M double mutants

Haoyang Zhang, Wenkui Wu, Chao Feng et al. · European Journal of Medicinal Chemistry · 2017 · 38 citations · Full text

L858r/t790m Double Mutants, Vivo Evaluation, Sar Discussion +6

Discovery of a novel dipeptidyl boronic acid proteasome inhibitor for the treatment of multiple myeloma and triple-negative breast cancer

Meng Lei, Huayun Feng, Enhe Bai et al. · Organic & Biomolecular Chemistry · 2018 · 32 citations

Breast Oncology, β5 Subunit, Immunotherapeutics +17

3D-QSAR-aided design, synthesis, in vitro and in vivo evaluation of dipeptidyl boronic acid proteasome inhibitors and mechanism studies

Meng Lei, Huayun Feng, Cheng Wang et al. · Bioorganic & Medicinal Chemistry · 2016 · 16 citations · Full text

3D-qsar-aided Design, Combinatorial Chemistry, Medicinal Chemistry +11

Design, synthesis and docking studies of novel dipeptidyl boronic acid proteasome inhibitors constructed from αα- and αβ-amino acids

Jingmiao Shi, Meng Lei, Wenkui Wu et al. · Bioorganic & Medicinal Chemistry Letters · 2016 · 12 citations · Full text

Design, synthesis, in vitro and in vivo evaluation, and structure-activity relationship (SAR) discussion of novel dipeptidyl boronic acid proteasome inhibitors as orally available anti-cancer agents for the treatment of multiple myeloma and mechanism studies

Meng Lei, Huayun Feng, Enhe Bai et al. · Bioorganic & Medicinal Chemistry · 2018 · 10 citations · Full text