Concepedia

Grandiflorenic acid promotes death of promastigotes via apoptosis-like mechanism and affects amastigotes by increasing total iron bound capacity

Bruna Taciane da Silva Bortoleti, Manoela Daiele Gonçalves, Fernanda Tomiotto‐Pellissier, Milena Menegazzo Miranda-Sapla, João Paulo Assolini, Amanda Cristina Machado Carloto, Priscila Goes Camargo, Ian Lucas Alves Cardoso, Andréa Name Colado Simão, Nilton Syogo Arakawa,

Phytomedicine · 2018 · 27 citations · 23 references

DOI

Concepts

References

23

Molecular Properties That Influence the Oral Bioavailability of Drug Candidates

Daniel F. Veber, Stephen R. Johnson, Hung‐Yuan Cheng et al. · Journal of Medicinal Chemistry · 2002 · 7.8K citations

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Lead- and drug-like compounds: the rule-of-five revolution

Christopher A. Lipinski · Drug Discovery Today Technologies · 2004 · 5.8K citations

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Increase in Cytosolic Ca2+ Levels through the Activation of Non-selective Cation Channels Induced by Oxidative Stress Causes Mitochondrial Depolarization Leading to Apoptosis-like Death in Leishmania donovaniPromastigotes

Sikha Bettina Mukherjee, Manika Das, Ganapasam Sudhandiran et al. · Journal of Biological Chemistry · 2002 · 205 citations · Full text

Apoptotic markers in protozoan parasites

Antonio Jiménez-Ruı́z, Juan F. Álzate, Ewan T. MacLeod et al. · Parasites & Vectors · 2010 · 140 citations · Full text

Induction of Mitochondrial Dysfunction and Oxidative Stress in Leishmania donovani by Orally Active Clerodane Diterpene

Manoj Kathuria, Arindam Bhattacharjee, Koneni V. Sashidhara et al. · Antimicrobial Agents and Chemotherapy · 2014 · 98 citations · Full text