Manoela Daiele Gonçalves

Dehydroabietic acid isolated from Pinus elliottii exerts in vitro antileishmanial action by pro-oxidant effect, inducing ROS production in promastigote and downregulating Nrf2/ferritin expression in amastigote forms of Leishmania amazonensis

Manoela Daiele Gonçalves, Bruna Taciane da Silva Bortoleti, Fernanda Tomiotto‐Pellissier et al. · Fitoterapia · 2018 · 41 citations

Nrf2/ferritin Expression, Biosynthesis, Vitro Antileishmanial Action +10

Caffeic acid has antipromastigote activity by apoptosis-like process; and anti-amastigote by TNF-α/ROS/NO production and decreased of iron availability

Bruna Taciane da Silva Bortoleti, Fernanda Tomiotto‐Pellissier, Manoela Daiele Gonçalves et al. · Phytomedicine · 2018 · 32 citations

Inflammation, Apoptosis-like Process, Iron Availability +11

Grandiflorenic acid promotes death of promastigotes via apoptosis-like mechanism and affects amastigotes by increasing total iron bound capacity

Bruna Taciane da Silva Bortoleti, Manoela Daiele Gonçalves, Fernanda Tomiotto‐Pellissier et al. · Phytomedicine · 2018 · 27 citations

Reductive Stress, Grandiflorenic Acid, Biochemistry +12

Trans-chalcone induces death by autophagy mediated by p53 up-regulation and β-catenin down-regulation on human hepatocellular carcinoma HuH7.5 cell line

Elaine da Silva Siqueira, Virgínia Márcia Concato, Fernanda Tomiotto‐Pellissier et al. · Phytomedicine · 2020 · 26 citations · Full text

Tumor Biology, Cell Autophagy, β-Catenin Down-regulation +13

Solidagenone acts on promastigotes of L. amazonensis by inducing apoptosis-like processes on intracellular amastigotes by IL-12p70/ROS/NO pathway activation

Bruna Taciane da Silva Bortoleti, Manoela Daiele Gonçalves, Fernanda Tomiotto‐Pellissier et al. · Phytomedicine · 2021 · 20 citations

Biosynthesis, Biochemistry, Apoptosis +9