Publication | Closed Access
Adventures in Atropisomerism: Total Synthesis of a Complex Active Pharmaceutical Ingredient with Two Chirality Axes
58
Citations
35
References
2018
Year
Medicinal ChemistryNatural Product SynthesisEnantioselective SynthesisMultiple Chirality AxesNatural SciencesMedicineCompound 1AChirality AxesTotal SynthesisOrganic ChemistryStereoselective SynthesisChemistryPharmacologyAsymmetric CatalysisSynthetic ChemistryBiomolecular EngineeringDrug DiscoveryConcise Total Synthesis
A strategy to prepare compounds with multiple chirality axes, which has led to a concise total synthesis of compound 1A with complete stereocontrol, is reported.
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