Paul C. Lobben

The Evolution of High-Throughput Experimentation in Pharmaceutical Development and Perspectives on the Future

Steven M. Mennen, Carolina Alhambra, C. Liana Allen et al. · Organic Process Research & Development · 2019 · 535 citations

Pharmaceutical Research, Pharmaceutical Innovation, Hit Identification +25

π-Facial Diastereoselection in the 1,2-Addition of Allylmetal Reagents to 2-Methoxycyclohexanone and Tetrahydrofuranspiro-(2-cyclohexanone)

Leo A. Paquette, Paul C. Lobben · Journal of the American Chemical Society · 1996 · 72 citations

Indium Catalysis, Engineering, Biochemistry +12

Adventures in Atropisomerism: Total Synthesis of a Complex Active Pharmaceutical Ingredient with Two Chirality Axes

Gregory L. Beutner, Ronald Carrasquillo‐Flores, Peng Geng et al. · Organic Letters · 2018 · 58 citations

Medicinal Chemistry, Natural Product Synthesis, Enantioselective Synthesis +15

Evaluation of Chelation Effects Operative during Diastereoselective Addition of the Allylindium Reagent to 2- and 3-Hydroxycyclohexanones in Aqueous, Organic, and Mixed Solvent Systems

Leo A. Paquette, Paul C. Lobben · The Journal of Organic Chemistry · 1998 · 46 citations

3-Hydroxycyclohexanones 1−8, Chelation Effects Operative, Chemical Engineering +14

Allylindation of 6-Substituted 2-Hydroxy-1-tetralones in Aqueous and Organic Media. Stereochemistry and Competition Studies

Paul C. Lobben, Leo A. Paquette · The Journal of Organic Chemistry · 1998 · 30 citations

Engineering, Organic Chemistry, Chemistry +16