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Design, synthesis and anticancer evaluation of 1H-pyrazolo[3,4-d]pyrimidine derivatives as potent EGFRWT and EGFRT790M inhibitors and apoptosis inducers

Tumor BiologyMedicinal ChemistryEgfrt790m InhibitorsMedicinePotent EgfrwtPharmacologyPharmacological AgentAnticancer EvaluationPharmacotherapyAnti-cancer AgentDrug DevelopmentOncologyRadiation OncologyPharmaceutical ChemistryCancer ResearchDrug Discovery