Ashraf H. Bayoumi

Design, synthesis and anticancer evaluation of 1H-pyrazolo[3,4-d]pyrimidine derivatives as potent EGFRWT and EGFRT790M inhibitors and apoptosis inducers

Ahmed A. Abdel Gaber, Ashraf H. Bayoumi, Ahmed El-morsy et al. · Bioorganic Chemistry · 2018 · 134 citations

Medicine, Medicinal Chemistry, Oncology +17

Design, Synthesis and Cytotoxic Evaluation of Novel Chalcone Derivatives Bearing Triazolo[4,3-a]-quinoxaline Moieties as Potent Anticancer Agents with Dual EGFR Kinase and Tubulin Polymerization Inhibitory Effects

Mohamed Alswah, Ashraf H. Bayoumi, Kamal M. El‐Gamal et al. · Molecules · 2017 · 110 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +10

Pharmacophore‐linked pyrazolo[3,4‐<i>d</i>]pyrimidines as EGFR‐TK inhibitors: Synthesis, anticancer evaluation, pharmacokinetics, and in silico mechanistic studies

Ahmed A. Abdel Gaber, Ahmed El-morsy, Farag F. Sherbiny et al. · Archiv der Pharmazie · 2021 · 74 citations

Pharmacy, Medicinal Chemistry, Pharmacology +17

Isatin-Schiff's base and chalcone hybrids as chemically apoptotic inducers and EGFR inhibitors; design, synthesis, anti-proliferative activities and in silico evaluation

Eman A. Fayed, Rogy R. Ezz Eldin, Ahmed B. M. Mehany et al. · Journal of Molecular Structure · 2021 · 69 citations

Pharmacy, Medicinal Chemistry, Oncology +13

From triazolophthalazines to triazoloquinazolines: A bioisosterism-guided approach toward the identification of novel PCAF inhibitors with potential anticancer activity

Mohamed H. El‐Shershaby, Adel Ghiaty, Ashraf H. Bayoumi et al. · Bioorganic & Medicinal Chemistry · 2021 · 67 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +14