Concepedia

The E3 ligase C-CBL inhibits cancer cell migration by neddylating the proto-oncogene c-Src

Gun Woo Lee, Jun Bum Park, Sung Yeon Park, Jieun Seo, Seung-Hyun Shin, Jong‐Wan Park, Sang Jeong Kim, Masatoshi Watanabe, Yang‐Sook Chun

Oncogene · 2018 · 42 citations · 32 references

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References

32

An inhibitor of NEDD8-activating enzyme as a new approach to treat cancer

Teresa A. Soucy, Peter G. Smith, Michael A. Milhollen et al. · Nature · 2009 · 2K citations

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Discovery of a Novel, Potent, and Src Family-selective Tyrosine Kinase Inhibitor

Jeffrey H. Hanke, Joseph P. Gardner, Robert L. Dow et al. · Journal of Biological Chemistry · 1996 · 2K citations · Full text

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Mdm2-Mediated NEDD8 Conjugation of p53 Inhibits Its Transcriptional Activity

Dimitris P. Xirodimas, Mark K. Saville, Jean‐Christophe Bourdon et al. · Cell · 2004 · 560 citations · Full text

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Dynamics of Cullin-RING Ubiquitin Ligase Network Revealed by Systematic Quantitative Proteomics

Eric J. Bennett, A. John Rush, Steven P. Gygi et al. · Cell · 2010 · 409 citations · Full text

, , +14

Gain-of-function of mutated C-CBL tumour suppressor in myeloid neoplasms

Masashi Sanada, Takahiro Suzuki, Lee‐Yung Shih et al. · Nature · 2009 · 393 citations

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