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Medicine, Genetics, Oncology +17

Carbonic anhydrase inhibitors: Sulfonamides as antitumor agents?

Claudiu T. Supuran, Fabrizio Briganti, Silvia Tilli et al. · Bioorganic & Medicinal Chemistry · 2001 · 275 citations

Medicine, Medicinal Chemistry, Oncology +12

Carbonic anhydrase inhibitors: E7070, a sulfonamide anticancer agent, potently inhibits cytosolic isozymes I and II, and transmembrane, tumor-associated isozyme IX

Francesco Abbate, Angela Casini, Takashi Owa et al. · Bioorganic & Medicinal Chemistry Letters · 2003 · 260 citations · Full text

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Mechanism of action of E7010, an orally active sulfonamide antitumor agent: inhibition of mitosis by binding to the colchicine site of tubulin.

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