Concepedia
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Publications
20
Citations
3.3K
H-Index
18
Active since
2004
Affiliations
National University of Singapore(Current)
National University Cancer Institute, Singapore
Vall d'Hebron Institute of Oncology
Massachusetts General Hospital
The Netherlands Cancer Institute
Pieter J.A. Eichhorn is an author at National University of Singapore specializing in medicine, cell biology, and cell signaling.
Top concepts
MedicineCell BiologyCell SignalingTumor BiologyCancer BiologySystems BiologyCancer ResearchGene ExpressionRadiation OncologySignal Transduction
Publications per year
2004–2020
NVP-BEZ235, a Dual PI3K/mTOR Inhibitor, Prevents PI3K Signaling and Inhibits the Growth of Cancer Cells with Activating PI3K Mutations
Violeta Serra, Ben Markman, Maurizio Scaltriti et al. · Cancer Research · 2008 · 795 citations · Full text
PI3K inhibition results in enhanced HER signaling and acquired ERK dependency in HER2-overexpressing breast cancer
Violeta Serra, Maurizio Scaltriti, Ludmila Prudkin et al. · Oncogene · 2011 · 530 citations · Full text
Phosphatidylinositol 3-Kinase Hyperactivation Results in Lapatinib Resistance that Is Reversed by the mTOR/Phosphatidylinositol 3-Kinase Inhibitor NVP-BEZ235
Pieter J.A. Eichhorn, Magüi Gili, Maurizio Scaltriti et al. · Cancer Research · 2008 · 483 citations · Full text
USP15 stabilizes TGF-β receptor I and promotes oncogenesis through the activation of TGF-β signaling in glioblastoma
Pieter J.A. Eichhorn, Laura Rodón, Alba Gonzàlez-Juncà et al. · Nature Medicine · 2012 · 396 citations
Tgf-β Receptor, Signaling Pathway, Medicine +6
Cyclin E amplification/overexpression is a mechanism of trastuzumab resistance in HER2 <sup>+</sup> breast cancer patients
Maurizio Scaltriti, Pieter J.A. Eichhorn, Javier Cortés et al. · Proceedings of the National Academy of Sciences · 2011 · 320 citations
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