BCL-2 selective inhibitor ABT-199 primes rhabdomyosarcoma cells to histone deacetylase inhibitor-induced apoptosis

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Bid-induced Conformational Change of Bax Is Responsible for Mitochondrial Cytochrome c Release during Apoptosis

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The MCL1 inhibitor S63845 is tolerable and effective in diverse cancer models

András Kotschy, Zoltán Szlávik, James B. Murray et al. · Nature · 2016 · 1K citations

Mcl1 Inhibitor S63845, Systems Biology, Oncology +11

Selective BCL-2 Inhibition by ABT-199 Causes On-Target Cell Death in Acute Myeloid Leukemia

Rongqing Pan, Leah J. Hogdal, Juliana M. Benito et al. · Cancer Discovery · 2013 · 717 citations · Full text

Cell Damage-induced Conformational Changes of the Pro-Apoptotic Protein Bak In Vivo Precede the Onset of Apoptosis

Gareth Griffiths, Laurence Dubrez, Clive P. Morgan et al. · The Journal of Cell Biology · 1999 · 479 citations · Full text

Apoptosis, Immunology, Molecular Biology +22