Cytokine Secretion and Pyroptosis of Thyroid Follicular Cells Mediated by Enhanced NLRP3, NLRP1, NLRC4, and AIM2 Inflammasomes Are Associated With Autoimmune Thyroiditis - Concepedia

Concepedia

Publication | Open Access

Cytokine Secretion and Pyroptosis of Thyroid Follicular Cells Mediated by Enhanced NLRP3, NLRP1, NLRC4, and AIM2 Inflammasomes Are Associated With Autoimmune Thyroiditis

DOI Full Paper Access

161

Citations

19

References

2018

Year

Qingling Guo, Ying Wu, Yuanyuan Hou, Yongping Liu, Tingting Liu, Hao Zhang, Chenling Fan, Haixia Guan, Yushu Li, Zhongyan Shan,

Frontiers in Immunology

Abstract

Our work has demonstrated for the first time that multiple inflammasomes are associated with AIT pathogenesis. The identified NLRP3, NLRP1, NLRC4, AIM2 inflammasomes and their downstream cytokines may represent potential therapeutic targets and biomarkers of AIT.

References

	Year	Citations

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