Prateep Pakavathkumar

Neuronal NLRP1 inflammasome activation of Caspase-1 coordinately regulates inflammatory interleukin-1-beta production and axonal degeneration-associated Caspase-6 activation

Vandana Kaushal, Rebecca Dye, Prateep Pakavathkumar et al. · Cell Death and Differentiation · 2015 · 308 citations

Life Sciences, Neurobiology, Neuroscience +16

Impact of the NGF Maturation and Degradation Pathway on the Cortical Cholinergic System Phenotype

S.T.M. Allard, Wanda León, Prateep Pakavathkumar et al. · Journal of Neuroscience · 2012 · 102 citations · Full text

Life Sciences, Neurobiology, Neuroscience +17

Caspase-6 activity in the CA1 region of the hippocampus induces age-dependent memory impairment

Andréa C. LeBlanc, Jasmine Ramcharitar, Veronica M. Afonso et al. · Cell Death and Differentiation · 2014 · 52 citations · Full text

Life Sciences, Neurobiology, Neuroscience +15

Methylene Blue Inhibits Caspases by Oxidation of the Catalytic Cysteine

Prateep Pakavathkumar, Gyanesh Sharma, Vikas Kaushal et al. · Scientific Reports · 2015 · 38 citations · Full text

Life Sciences, Biochemistry, Pharmacology +12

Caspase vinyl sulfone small molecule inhibitors prevent axonal degeneration in human neurons and reverse cognitive impairment in Caspase-6-overexpressing mice

Prateep Pakavathkumar, Anastasia Noël, Clotilde Lecrux et al. · Molecular Neurodegeneration · 2017 · 29 citations · Full text

Life Sciences, Neuroscience, Pharmacology +14