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Kinetic and structural comparison of a protein’s cotranslational folding and refolding pathways

Avi J. Samelson, Eric R. Bolin, Shawn M. Costello, Ajeet K. Sharma, Edward P. O’Brien, Susan Marqusee

Science Advances · 2018 · 80 citations · 34 references

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Abstract

Kinetic and structural comparison of the cotranslational and refolding pathways of HaloTag reveals how translation reroutes the folding pathway to avoid aggregation.

References

34

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Evolutionary conservation of codon optimality reveals hidden signatures of cotranslational folding

Sebastian Pechmann, Judith Frydman · Nature Structural & Molecular Biology · 2012 · 519 citations · Full text

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The Ribosome Modulates Nascent Protein Folding

Christian Kaiser, Daniel Goldman, John D. Chodera et al. · Science · 2011 · 314 citations · Full text