Concepedia

Discovery of a novel olefin derivative as a highly potent and selective acetyl-CoA carboxylase 2 inhibitor with in vivo efficacy

Yuji Nishiura, Akira Matsumura, Naotake Kobayashi, Atsuyuki Shimazaki, Shingo Sakamoto, Naohisa Kitade, Yutaka Tonomura, Akira Ino, Takayuki Okuno

Bioorganic & Medicinal Chemistry Letters · 2018 · 14 citations · 21 references

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The Use of Diethyl Azodicarboxylate and Triphenylphosphine in Synthesis and Transformation of Natural Products

Oyo Mitsunobu · Synthesis · 1981 · 4.1K citations

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Palladium(0)-Catalyzed Cross-Coupling Reaction of Alkoxydiboron with Haloarenes: A Direct Procedure for Arylboronic Esters

Tatsuo Ishiyama, Miki Murata, Norio Miyaura · The Journal of Organic Chemistry · 1995 · 1.5K citations

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Continuous Fatty Acid Oxidation and Reduced Fat Storage in Mice Lacking Acetyl-CoA Carboxylase 2

Lutfi Abu-Elheiga, Martin M. Matzuk, Khaled A.H. Abo-Hashema et al. · Science · 2001 · 890 citations

Lipophilicity in drug discovery

Michael J. Waring · Expert Opinion on Drug Discovery · 2010 · 824 citations

Hydrozirconation. Organic synthesis via organozirconium intermediates. Synthesis and rearrangement of alkylzirconium(IV) complexes and their reaction with electrophiles

Donald W. Hart, Jeffrey Schwartz · Journal of the American Chemical Society · 1974 · 422 citations

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