Plasma miR‐208 as a useful biomarker for drug‐induced cardiotoxicity in rats

Yoko Nishimura, Chiaki Kondo, Yuji Morikawa, +4

Journal of Applied Toxicology

Evaluation of the usefulness of urinary biomarkers for nephrotoxicity in rats

Yutaka Tonomura, Noriko Tsuchiya, Mikinori Torii, +1

Toxicology

UrologyRenal FunctionMedicinePhysiologyRenal Pathology +7

Evaluation of the usefulness of biomarkers for cardiac and skeletal myotoxicity in rats

Yutaka Tonomura, Yoko Mori, Mikinori Torii, +1

Toxicology

Skeletal MyotoxicityCardiomyopathyHeart FailureCardiac MuscleCardiovascular Disease +8

Biomarker panel of cardiac and skeletal muscle troponins, fatty acid binding protein 3 and myosin light chain 3 for the accurate diagnosis of cardiotoxicity and musculoskeletal toxicity in rats

Yutaka Tonomura, Shuuichi Matsushima, Emi Kashiwagi, +6

Toxicology

Cardiac MuscleCardiomyopathyHeart FailureCardiovascular DiseasePhysiology +7

Identification of metabolomic biomarkers for drug‐induced acute kidney injury in rats

Takeki Uehara, Akira Horinouchi, Yuji Morikawa, +7

Journal of Applied Toxicology

Amphotericin B-induced nephrotoxicity: characterization of blood and urinary biochemistry and renal morphology in mice

Yutaka Tonomura, E. Yamamoto, Chiaki Kondo, +4

Human & Experimental Toxicology

Renal PathologyOxidative StressUrinary BiochemistryMolecular PharmacologyRenal Function +15

Involvement of neutrophil gelatinase-associated lipocalin and osteopontin in renal tubular regeneration and interstitial fibrosis after cisplatin-induced renal failure

Emi Kashiwagi, Yutaka Tonomura, Chiaki Kondo, +9

Experimental and Toxicologic Pathology

InflammationUrologyFibrosisRenal FunctionMedicine +12

Identification of potential genomic biomarkers for early detection of chemically induced cardiotoxicity in rats

Yoko Mori, Chiaki Kondo, Yutaka Tonomura, +2

Toxicology

InflammationCardiomyopathyHeart FailureInduced CardiotoxicityCardiovascular Disease +10

Decrease in urinary creatinine in acute kidney injury influences diagnostic value of urinary biomarker-to-creatinine ratio in rats

Yutaka Tonomura, Takeki Uehara, E. Yamamoto, +2

Toxicology

UrologyRenal FunctionPhysiologyUrinary CreatinineRenal Inflammation +5

Structure-Based Approaches to Improving Selectivity through Utilizing Explicit Water Molecules: Discovery of Selective β-Secretase (BACE1) Inhibitors over BACE2

Kazuki Fujimoto, Shuhei Yoshida, Genta Tadano, +14

Journal of Medicinal Chemistry