Naotake Kobayashi

Discovery of the Orally Effective Thyrotropin-Releasing Hormone Mimetic: 1-{<i>N</i>-[(4<i>S</i>,5<i>S</i>)-(5-Methyl-2-oxooxazolidine-4-yl)carbonyl]-3-(thiazol-4-yl)-<scp>l</scp>-alanyl}-(2<i>R</i>)-2-methylpyrrolidine Trihydrate (Rovatirelin Hydrate)

Naotake Kobayashi, Norihito Sato, Yuko Fujimura et al. · ACS Omega · 2018 · 15 citations · Full text

Discovery of a novel olefin derivative as a highly potent and selective acetyl-CoA carboxylase 2 inhibitor with in vivo efficacy

Yuji Nishiura, Akira Matsumura, Naotake Kobayashi et al. · Bioorganic & Medicinal Chemistry Letters · 2018 · 14 citations · Full text

Medicinal Chemistry, Pharmaceutical Science, Biochemistry +10

Stereocontrolled Synthesis of Dithymidine Phosphorothioates by Use of a Functionalized 5′- Protecting Group Bearing an Imidazole Residue

Takeshi Wada, Naotake Kobayashi, T. MORI et al. · Nucleosides and Nucleotides · 1998 · 11 citations

Pyrrolinone derivatives as a new class of P2X3 receptor antagonists. Part 1: Initial structure-activity relationship studies of a hit from a high throughput screening

Hiroyuki Tobinaga, Takayuki Kameyama, Miho Oohara et al. · Bioorganic & Medicinal Chemistry Letters · 2017 · 11 citations · Full text

Drug Target, Biochemistry, Medicine +9