Concepedia

Dynamic allostery can drive cold adaptation in enzymes

Harry Saavedra, James O. Wrabl, Jeremy A. Anderson, Jing Li, Vincent J. Hilser

Nature · 2018 · 228 citations · 25 references

DOI

Concepts

References

25

The Activated Complex in Chemical Reactions

Henry Eyring · The Journal of Chemical Physics · 1935 · 5.7K citations

, , +12

A hierarchy of timescales in protein dynamics is linked to enzyme catalysis

Katherine A. Henzler‐Wildman, Ming Lei, Vu Thai et al. · Nature · 2007 · 1.1K citations

, , +12

Development of transition-state theory

Keith J. Laidler, M. Christine King · The Journal of Physical Chemistry · 1983 · 1.1K citations

, , +7

Intrinsic motions along an enzymatic reaction trajectory

Katherine A. Henzler‐Wildman, Vu Thai, Ming Lei et al. · Nature · 2007 · 910 citations

, , +14

Structure of the complex between adenylate kinase from Escherichia coli and the inhibitor Ap5A refined at 1.9 Å resolution

Christoph W. Müller, Georg E. Schulz · Journal of Molecular Biology · 1992 · 531 citations

, , +11