Concepedia

Dynamic Allostery

Dynamic Allostery is a type of allosteric regulation in which conformational dynamics, rather than structural changes, transmit regulatory effects between distant sites in a biomolecule, enabling functional modulation without detectable equilibrium shifts in protein structure.

77

Publications

4.4K

Citations

351

Authors

162

Institutions

Publications per year

2017–2026

41

Parents

Publications

77

Dynamically driven protein allostery

Nataliya Popovych, Shangjin Sun, Richard H. Ebright et al. · Nature Structural & Molecular Biology · 2006 · 635 citations · Full text

, , +11

Hidden dynamic allostery in a PDZ domain

Chad M. Petit, Jun Zhang, Paul J. Sapienza et al. · Proceedings of the National Academy of Sciences · 2009 · 342 citations · Full text

, , +17

A Cholesterol-Based Allostery Model of T Cell Receptor Phosphorylation

Mahima Swamy, Katharina Beck-García, Esmeralda Beck-Garcìa et al. · Immunity · 2016 · 243 citations · Full text

, , +14

Dynamic allostery can drive cold adaptation in enzymes

Harry Saavedra, James O. Wrabl, Jeremy A. Anderson et al. · Nature · 2018 · 228 citations

, , +13

Conformational Rigidity and Protein Dynamics at Distinct Timescales Regulate PTP1B Activity and Allostery

M.S. Choy, Yang Li, Luciana E. S. F. Machado et al. · Molecular Cell · 2017 · 136 citations · Full text

, , +16

1–5 of 77

Authors

351

  1. TM
    Tom McLeish

    University of Leeds, United Kingdom

    6 publications · 301 citations

    6

    h-index

  2. SB
    S. Banu Ozkan

    Arizona State University, United States

    5 publications · 206 citations

    5

    h-index

  3. HW
    Hongwei Wu

    Sichuan Agricultural University, China

    3 publications · 158 citations

    3

    h-index

  4. MJ
    Martin J. Cann

    Durham University, United Kingdom

    3 publications · 152 citations

    3

    h-index

  5. TL
    Thomas L. Rodgers

    University of Manchester, United Kingdom

    3 publications · 152 citations

    3

    h-index

1–5 of 351

Institutions

162

  1. Arizona State University

    Tempe, United States

    6 h-index

    18 publications

    624 citations

  2. University of Leeds

    Leeds, United Kingdom

    4 h-index

    9 publications

    349 citations

  3. Institute of Structural and Molecular Biology

    London, United Kingdom

    4 h-index

    12 publications

    328 citations

  4. Indiana University Bloomington

    Bloomington, United States

    3 h-index

    15 publications

    790 citations

  5. Durham University

    Durham, United Kingdom

    3 h-index

    17 publications

    938 citations

  6. University of York

    York, United Kingdom

    2 h-index

    4 publications

    224 citations

  7. University of Canterbury

    Christchurch, New Zealand

    2 h-index

    8 publications

    260 citations

  8. University of Colorado Denver

    Denver, United States

    2 h-index

    3 publications

    184 citations

1–8 of 162

Venues

  1. Journal of Molecular Biology

    JMB · 8 publications · 276 citations

    8

    h-index

  2. Biophysical Journal

    7 publications · 267 citations

    7

    h-index

  3. Proceedings of the National Academy of Sciences

    PNAS · 7 publications · 804 citations

    7

    h-index

  4. PLoS Computational Biology

    4 publications · 149 citations

    4

    h-index

  5. Chemical Science

    3 publications · 81 citations

    3

    h-index

1–5