PAMAM dendrimers as efficient drug and gene delivery nanosystems for cancer therapy

A new concept for macromolecular therapeutics in cancer chemotherapy: mechanism of tumoritropic accumulation of proteins and the antitumor agent smancs.

Yasuhiro Matsumura, Hiroshi Maeda · PubMed · 1986 · 6.8K citations

Medicine, Oncology, Pharmacology +12

Poly(amidoamine) (PAMAM) dendrimers: from biomimicry to drug delivery and biomedical applications

Roseita Esfand, Donald A. Tomalia · Drug Discovery Today · 2001 · 1.5K citations

Pharmacy, Pharmaceutics, Pharmacology +14

Dendrimers: synthesis, applications, and properties

Elham Abbasi, Sedigheh Fekri Aval, Abolfazl Akbarzadeh et al. · Nanoscale Research Letters · 2014 · 1.2K citations · Full text

Pharmacy, Medicinal Chemistry, Molecular Pharmaceutics +14

Polyamidoamine cascade polymers mediate efficient transfection of cells in culture

Jean Haensler, Francis C. Szoka · Bioconjugate Chemistry · 1993 · 1.2K citations

Life Sciences, Biotechnology, Molecular Biology +17

Birth of a new macromolecular architecture: dendrimers as quantized building blocks for nanoscale synthetic polymer chemistry

Donald A. Tomalia · Progress in Polymer Science · 2005 · 1.1K citations

Natural Sciences, Chemistry, Materials Science +16