Role of p53/miR-155-5p/sirt1 loop in renal tubular injury of diabetic kidney disease

Negative Control of p53 by Sir2α Promotes Cell Survival under Stress

Jianyuan Luo, Anatoly Nikolaev, Shin‐ichiro Imai et al. · Cell · 2001 · 2.1K citations · Full text

Cell Regulation, Cell Signaling, Apoptosis +9

Calorie Restriction Promotes Mammalian Cell Survival by Inducing the SIRT1 Deacetylase

Haim Cohen, Christine Miller, Kevin J. Bitterman et al. · Science · 2004 · 1.9K citations

Anti-aging, Cell Death, Cell Loss +20

The mitochondria-targeted antioxidant MitoQ ameliorated tubular injury mediated by mitophagy in diabetic kidney disease via Nrf2/PINK1

Li Xiao, Xiaoxuan Xu, Fan Zhang et al. · Redox Biology · 2016 · 547 citations · Full text

Renal tubular Sirt1 attenuates diabetic albuminuria by epigenetically suppressing Claudin-1 overexpression in podocytes

Kazuhiro Hasegawa, Shu Wakino, Petra Šimić et al. · Nature Medicine · 2013 · 464 citations · Full text

Diabetic Albuminuria, Urology, Renal Tubular Sirt1 +9

Autophagy Protects the Proximal Tubule from Degeneration and Acute Ischemic Injury

Tomonori Kimura, Yoshitsugu Takabatake, Atsushi Takahashi et al. · Journal of the American Society of Nephrology · 2011 · 448 citations · Full text

Mitophagy, Apoptosis, Immunology +27