Concepedia

The standardized Korean Red Ginseng extract and its ingredient ginsenoside Rg3 inhibit manifestation of breast cancer stem cell–like properties through modulation of self-renewal signaling

Jisun Oh, Hyo‐Jin Yoon, Jeong‐Hoon Jang, Do‐Hee Kim, Young‐Joon Surh

Journal of Ginseng Research · 2018 · 48 citations · 41 references

DOIFull text

Open access

Abstract

This study suggests that Rg3 has a therapeutic potential targeting breast cancer stem cells.

References

41

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Lindsey A. Torre, Freddie Bray, Rebecca L. Siegel et al. · CA A Cancer Journal for Clinicians · 2015 · 27.2K citations · Full text

ALDH1 Is a Marker of Normal and Malignant Human Mammary Stem Cells and a Predictor of Poor Clinical Outcome

Christophe Ginestier, Min Hee Hur, Emmanuelle Charafe‐Jauffret et al. · Cell stem cell · 2007 · 4K citations · Full text

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HIF-1-mediated expression of pyruvate dehydrogenase kinase: A metabolic switch required for cellular adaptation to hypoxia

Jung‐whan Kim, Irina Tchernyshyov, Gregg L. Semenza et al. · Cell Metabolism · 2006 · 3.8K citations · Full text

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Bmi-1 is required for maintenance of adult self-renewing haematopoietic stem cells

In-Kyung Park, Dalong Qian, Mark J. Kiel et al. · Nature · 2003 · 1.8K citations · Full text

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Hedgehog Signaling and Bmi-1 Regulate Self-renewal of Normal and Malignant Human Mammary Stem Cells

Suling Liu, Gabriela Dontu, Ilia D. Mantle et al. · Cancer Research · 2006 · 1.2K citations · Full text