Concepedia

Inactivation of deubiquitinase CYLD enhances therapeutic antibody production in Chinese hamster ovary cells

Yafang Lu, Qin Zhou, Qianqian Han, Pengfei Wu, Lanlan Zhang, Lin Zhu, David T. Weaver, Changzhi Xu, Buchang Zhang

Applied Microbiology and Biotechnology · 2018 · 18 citations · 50 references

DOI

Concepts

References

50

Multiplex Genome Engineering Using CRISPR/Cas Systems

Le Cong, F. Ann Ran, David Cox et al. · Science · 2013 · 15.7K citations

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Genome engineering using the CRISPR-Cas9 system

F. Ann Ran, Patrick D. Hsu, Jason Wright et al. · Nature Protocols · 2013 · 11.7K citations · Full text

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The tumour suppressor CYLD negatively regulates NF-κB signalling by deubiquitination

Andrew Kovalenko, Christine Chable-Bessia, Giuseppina Cantarella et al. · Nature · 2003 · 1K citations

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Identification of a Molecular Signaling Network that Regulates a Cellular Necrotic Cell Death Pathway

Junichi Hitomi, Dana E. Christofferson, Aylwin Ng et al. · Cell · 2008 · 976 citations · Full text

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CYLD is a deubiquitinating enzyme that negatively regulates NF-κB activation by TNFR family members

Eirini Trompouki, Eudoxia Hatzivassiliou, Theodore Tsichritzis et al. · Nature · 2003 · 968 citations · Full text

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