Concepedia

Enrichment-triggered prodrug activation demonstrated through mitochondria-targeted delivery of doxorubicin and carbon monoxide

Yueqin Zheng, Xingyue Ji, Bingchen Yu, Kaili Ji, David Gallo, Eva Csizmadia, Mengyuan Zhu, Manjusha Roy Choudhury, Ladie Kimberly C. De La Cruz, Vayou Chittavong,

Nature Chemistry · 2018 · 313 citations · 41 references

DOIFull text

Open access

Concepts

References

41

Carbon monoxide has anti-inflammatory effects involving the mitogen-activated protein kinase pathway

Leo E. Otterbein, Fritz H. Bach, Jawed Alam et al. · Nature Medicine · 2000 · 2.1K citations

, , +12

Tetrazine Ligation: Fast Bioconjugation Based on Inverse-Electron-Demand Diels−Alder Reactivity

Melissa L. Blackman, Maksim Royzen, Joseph M. Fox · Journal of the American Chemical Society · 2008 · 1.6K citations · Full text

, , +12

Carbon Monoxide-Releasing Molecules

Roberto Motterlini, James Clark, Roberta Foresti et al. · Circulation Research · 2002 · 991 citations

, , +14

Tetrazine-Based Cycloadditions: Application to Pretargeted Live Cell Imaging

Neal K. Devaraj, Ralph Weissleder, Scott A. Hilderbrand · Bioconjugate Chemistry · 2008 · 840 citations · Full text

, , +16

Delivery of bioactive molecules to mitochondria <i>in</i> <i>vivo</i>

Robin A.J. Smith, Carolyn M. Porteous, Alison M. Gane et al. · Proceedings of the National Academy of Sciences · 2003 · 712 citations

, , +14