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349 - BMS-986165 is a Highly Potent and Selective Allosteric Inhibitor of TYK2, Blocks Il-12, IL-23 and type I Interferon Signaling and Provides for Robust Efficacy in Preclinical Models of Inflammatory Bowel Disease

InflammationChronic Inflammatory DiseasesSelective Allosteric InhibitorBlocks Il-12CytokineAllergyImmunologyImmune RegulationChronic InflammationImmune SurveillanceAutoimmunityImmune SystemHumoral ImmunityImmune-mediated Inflammatory DiseasesInnate ImmunityImmunotherapyMedicineInflammatory Disease