Cyclization of peptides with two chemical bridges affords large scaffold diversities

How proteins bind macrocycles

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Life Sciences, Biochemistry, Molecular Biology +10

Protein Modification, Bioconjugation, and Disulfide Bridging Using Bromomaleimides

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Life Sciences, Biochemistry, Bioorthogonal Chemistry +12

Ecallantide for the Treatment of Acute Attacks in Hereditary Angioedema

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Veterinary Medicine, Pharmacology, Pharmacotherapy +4

Rapid and Quantitative Cyclization of Multiple Peptide Loops onto Synthetic Scaffolds for Structural Mimicry of Protein Surfaces

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Life Sciences, Biochemistry, Biotechnology +15

Development of α-Helical Calpain Probes by Mimicking a Natural Protein–Protein Interaction

Hyunil Jo, Nataline Meinhardt, Yibing Wu et al. · Journal of the American Chemical Society · 2012 · 255 citations · Full text

Life Sciences, Biochemistry, Medicinal Chemistry +16