Genistein and daidzein induce apoptosis of colon cancer cells by inhibiting the accumulation of lipid droplets

Abstract

Our results demonstrated that GEN and DAI inhibit the accumulation of LDs by regulating LDs-related factors and lead to a final apoptosis of colon cancer cells. These results may provide important new insights into the possible molecular mechanisms of isoflavones in anti-obesity and anti-tumor functions.