Genetic alterations driving metastatic colony formation are acquired outside of the primary tumour in melanoma

Intratumor Heterogeneity and Branched Evolution Revealed by Multiregion Sequencing

Marco Gerlinger, Andrew J. Rowan, Stuart Horswell et al. · New England Journal of Medicine · 2012 · 7.6K citations · Full text

Final Version of 2009 AJCC Melanoma Staging and Classification

Charles M. Balch, Jeffrey E. Gershenwald, Seng-Jaw Soong et al. · Journal of Clinical Oncology · 2009 · 4.5K citations · Full text

Melanoma exosomes educate bone marrow progenitor cells toward a pro-metastatic phenotype through MET

Héctor Peinado, Maša Alečković, Simon Lavotshkin et al. · Nature Medicine · 2012 · 3.6K citations · Full text

Exosomes, Medicine, Melanoma +12

A comparison of the Two One-Sided Tests Procedure and the Power Approach for assessing the equivalence of average bioavailability

Donald J. Schuirmann · Journal of Pharmacokinetics and Biopharmaceutics · 1987 · 2.5K citations · Full text

Average Bioavailability, Health Outcome, Bioequivalence +8

Distant metastasis occurs late during the genetic evolution of pancreatic cancer

Shinichi Yachida, Siân Jones, Ivana Božić et al. · Nature · 2010 · 2.5K citations

Pancreatic Cancer, Distant Metastasis, Tumor Heterogeneity +8