Concepedia

Acetyl-CoA Carboxylase Inhibitor GS-0976 for 12 Weeks Reduces Hepatic De Novo Lipogenesis and Steatosis in Patients With Nonalcoholic Steatohepatitis

Eric Lawitz, Angie Coste, Fred Poordad, Naim Alkhouri, Nicole Loo, B. Mccolgan, Jacqueline M. Tarrant, Tuan Nguyen, Ling Han, Chuhan Chung,

Clinical Gastroenterology and Hepatology · 2018 · 215 citations · 23 references

DOI

Concepts

References

23

Sources of fatty acids stored in liver and secreted via lipoproteins in patients with nonalcoholic fatty liver disease

Kerry L. Donnelly, Coleman I. Smith, Sarah Jane Schwarzenberg et al. · Journal of Clinical Investigation · 2005 · 3.5K citations · Full text

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Pioglitazone, Vitamin E, or Placebo for Nonalcoholic Steatohepatitis

Arun J. Sanyal, Naga Chalasani, Kris V. Kowdley et al. · New England Journal of Medicine · 2010 · 3.3K citations · Full text

, , +7

Liver Fibrosis, but No Other Histologic Features, Is Associated With Long-term Outcomes of Patients With Nonalcoholic Fatty Liver Disease

Paul Angulo, David E. Kleiner, Sanne Dam‐Larsen et al. · Gastroenterology · 2015 · 3K citations · Full text

, , +12

Increased De Novo Lipogenesis Is a Distinct Characteristic of Individuals With Nonalcoholic Fatty Liver Disease

Jennifer E. Lambert, María A. Ramos-Román, Jeffrey D. Browning et al. · Gastroenterology · 2013 · 1.1K citations · Full text

, , +11

Single phosphorylation sites in Acc1 and Acc2 regulate lipid homeostasis and the insulin-sensitizing effects of metformin

Morgan D. Fullerton, Sandra Galić, Katarina Marcinko et al. · Nature Medicine · 2013 · 875 citations · Full text

, , +16