GalT‐<scp>KO</scp> pig lungs are highly susceptible to acute vascular rejection in baboons, which may be mitigated by transgenic expression of <scp>hCD</scp>47 on porcine blood vessels

Abstract

To our knowledge, this is the first evidence of histologically viable porcine lung grafts beyond 7 days in baboons. Our results indicate that GalT-KO pig lungs are highly susceptible to acute humoral rejection and that this may be mitigated by transgenic expression of hCD47.