Concepedia

Xenogeneic Rejection

Xenogeneic Rejection is a type of immune-mediated graft rejection that occurs when tissues or organs are transplanted between phylogenetically distant species, characterized by a vigorous and immediate host immune response primarily driven by preformed antibodies and complement activation.

754

Publications

35.4K

Citations

3.5K

Authors

730

Institutions

Publications per year

2017–2026

68

Parents

Publications

754

A role for CD95 ligand in preventing graft rejection

Donald Bellgrau, Daniel P. Gold, Helena Selawry et al. · Nature · 1995 · 1.2K citations

, , +17

Production of α1,3-Galactosyltransferase-Deficient Pigs

Carol J. Phelps, Chihiro Koike, Todd Vaught et al. · Science · 2003 · 1.1K citations

, , +15

Genetically Modified Porcine-to-Human Cardiac Xenotransplantation

Bartley P. Griffith, Corbin E. Goerlich, Avneesh K. Singh et al. · New England Journal of Medicine · 2022 · 672 citations · Full text

, , +16

Interaction of the natural anti-Gal antibody with α-galactosyl epitopes: a major obstacle for xenotransplantation in humans

Uri Galili · Immunology Today · 1993 · 661 citations

, , +15

Prolonged diabetes reversal after intraportal xenotransplantation of wild-type porcine islets in immunosuppressed nonhuman primates

Bernhard J. Hering, Martin Wijkstrom, Maria Hårdstedt et al. · Nature Medicine · 2006 · 548 citations

, , +16

1–5 of 754

Authors

3.5K

  1. JL
    Jeffrey L. Platt

    Mayo Clinic, United States

    31 publications · 2.3K citations

    25

    h-index

  2. DH
    David H. Sachs

    Massachusetts General Hospital, United States

    24 publications · 1.7K citations

    19

    h-index

  3. DK
    David K. C. Cooper

    Massachusetts General Hospital, United States

    21 publications · 1.1K citations

    17

    h-index

  4. DA
    David Ayares

    University of Pittsburgh, United States

    19 publications · 3.2K citations

    17

    h-index

  5. MS
    Megan Sykes

    Massachusetts General Hospital, United States

    19 publications · 1.1K citations

    16

    h-index

1–5 of 3.5K

Institutions

730

  1. Massachusetts General Hospital

    Boston, United States

    34 h-index

    271 publications

    20.6K citations

  2. Harvard University

    Cambridge, United States

    30 h-index

    258 publications

    17.2K citations

  3. Duke Medical Center

    Durham, United States

    20 h-index

    56 publications

    4.1K citations

  4. University of Minnesota

    Minneapolis, United States

    17 h-index

    93 publications

    12K citations

  5. Inserm

    Paris, France

    17 h-index

    126 publications

    4.3K citations

  6. Medizinische Hochschule Hannover

    Hanover, Germany

    16 h-index

    77 publications

    4.2K citations

  7. Duke University

    Durham, United States

    15 h-index

    54 publications

    2.4K citations

  8. Duke University Hospital

    Durham, United States

    15 h-index

    41 publications

    2.8K citations

1–8 of 730

Venues

  1. Transplantation

    156 publications · 7.7K citations

    49

    h-index

  2. Xenotransplantation

    84 publications · 3.1K citations

    33

    h-index

  3. PubMed

    Repository · 121 publications · 3.1K citations

    28

    h-index

  4. The Journal of Immunology

    JI · 31 publications · 1.8K citations

    23

    h-index

  5. American Journal of Transplantation

    14 publications · 1.1K citations

    14

    h-index

1–5