Sonic hedgehog signaling pathway promotes INSM1 transcription factor in neuroendocrine lung cancer

Classification of human lung carcinomas by mRNA expression profiling reveals distinct adenocarcinoma subclasses

Arindam Bhattacharjee, William G. Richards, Jane Staunton et al. · Proceedings of the National Academy of Sciences · 2001 · 2.6K citations · Full text

Engineering, Pathology, Cancer Death +17

Hedgehog signalling within airway epithelial progenitors and in small-cell lung cancer

D. Neil Watkins, David M. Berman, Scott G. Burkholder et al. · Nature · 2003 · 1.1K citations

Tumor Biology, Developmental Biology, Medicine +8

Phosphoinositide 3-kinase and Akt are essential for Sonic Hedgehog signaling

Natalia A. Riobo‐Del Galdo, Ke Lu, Xingbin Ai et al. · Proceedings of the National Academy of Sciences · 2006 · 432 citations · Full text

GDC-0449—A potent inhibitor of the hedgehog pathway

Kirk Robarge, Shirley A. Brunton, Georgette M. Castanedo et al. · Bioorganic & Medicinal Chemistry Letters · 2009 · 385 citations · Full text

Molecular Pharmacology, Signaling Pathway, Molecular Pathway +6

Human small-cell lung cancers show amplification and expression of the N-myc gene.

Marion M. Nau, Burke J. Brooks, D N Carney et al. · Proceedings of the National Academy of Sciences · 1986 · 293 citations · Full text

C-myc Gene, Pathology, Cancer Biology +16