Chiachen Chen

Leptin-induced growth of human ZR-75-1 breast cancer cells is associated with up-regulation of cyclin D1 and c-Myc and down-regulation of tumor suppressor p53 and p21WAF1/CIP1

Chiachen Chen, Yuan‐Ching Chang, Chien‐Liang Liu et al. · Breast Cancer Research and Treatment · 2006 · 123 citations

Breast Oncology, Cyclin D1, Tumor Suppressor P53 +10

Leptin stimulates ovarian cancer cell growth and inhibits apoptosis by increasing cyclin D1 and Mcl-1 expression via the activation of the MEK/ERK1/2 and PI3K/Akt signaling pathways

Chiachen Chen, Yuan‐Ching Chang, Michael S. Lan et al. · International Journal of Oncology · 2013 · 96 citations

Leptin induces proliferation and anti-apoptosis in human hepatocarcinoma cells by up-regulating cyclin D1 and down-regulating Bax via a Janus kinase 2-linked pathway

Chiachen Chen, Yuan‐Ching Chang, Chien‐Liang Liu et al. · Endocrine Related Cancer · 2007 · 90 citations · Full text

Sonic hedgehog signaling pathway promotes INSM1 transcription factor in neuroendocrine lung cancer

Chiachen Chen, Mary B. Breslin, Michael S. Lan · Cellular Signalling · 2018 · 33 citations

Cancer Research, Sonic Hedgehog, Medicine +9

Identification of an INSM1-binding site in the insulin promoter: negative regulation of the insulin gene transcription

Hongwei Wang, Michelle Muguira, Weidong Liu et al. · Journal of Endocrinology · 2008 · 24 citations · Full text