Regulation of Wnt Signaling and Embryo Patterning by an Extracellular Sulfatase

Gurtej K. Dhoot, Marcus K. Gustafsson, Xingbin Ai, +3

Science

QSulf1 remodels the 6-O sulfation states of cell surface heparan sulfate proteoglycans to promote Wnt signaling

Xingbin Ai, Anh-Tri Do, Olga Lozynska, +3

The Journal of Cell Biology

Phosphoinositide 3-kinase and Akt are essential for Sonic Hedgehog signaling

Natalia A. Riobo‐Del Galdo, Ke Lu, Xingbin Ai, +2

Proceedings of the National Academy of Sciences

QSulf1, a heparan sulfate 6- <i>O</i> -endosulfatase, inhibits fibroblast growth factor signaling in mesoderm induction and angiogenesis

Shouwen Wang, Xingbin Ai, Stephen Freeman, +4

Proceedings of the National Academy of Sciences

SULF1 and SULF2 regulate heparan sulfate-mediated GDNF signaling for esophageal innervation

Xingbin Ai, Toshio Kitazawa, Anh-Tri Do, +3

Development

GlycobiologyCellular PhysiologyInflammationHeparan Sulfate-mediated GdnfSignaling Pathway +15

Substrate Specificity and Domain Functions of Extracellular Heparan Sulfate 6-O-Endosulfatases, QSulf1 and QSulf2

Xingbin Ai, Anh-Tri Do, Marion Kusche‐Gullberg, +3

Journal of Biological Chemistry

Protein FunctionSignal TransductionSignaling PathwayBiochemistryNatural Sciences +12

Ventral Neural Progenitors Switch toward an Oligodendroglial Fate in Response to Increased Sonic Hedgehog (Shh) Activity: Involvement of Sulfatase 1 in Modulating Shh Signaling in the Ventral Spinal Cord

Cathy Danesin, Eric Agius, Nathalie Escalas, +4

Journal of Neuroscience

Sulfatase 1Cellular PhysiologySonic HedgehogSocial SciencesNeuroregeneration +15

Derivation of lung mesenchymal lineages from the fetal mesothelium requires hedgehog signaling for mesothelial cell entry

Radhika Dixit, Xingbin Ai, Alan Fine

Development

Organ DevelopmentCell SpecializationCellular PhysiologyEmbryologyTissue Development +20

Aspirin-triggered resolvin D1 is produced during self-resolving gram-negative bacterial pneumonia and regulates host immune responses for the resolution of lung inflammation

R.-E.E. Abdulnour, Ho Pan Sham, David N. Douda, +6

Mucosal Immunology

The Generation of Neuronal Heterogeneity in a Rat Sensory Ganglion

A Hall, Xingbin Ai, Georgia E. Hickman, +3

Journal of Neuroscience

NeurotransmissionCellular NeurobiologySensory SystemsCellular PhysiologySocial Sciences +19