Concepedia

Development and validation of a stability-indicating RP-HPLC method for simultaneous determination of dapagliflozin and saxagliptin in fixed-dose combination

Narendra Singh, Parveen Bansal, M. Maithani, Yashpal Singh Chauhan

New Journal of Chemistry · 2018 · 44 citations · 14 references

DOI

Concepts

Abstract

A simple and precise stability indicating method for the simultaneous estimation of dapagliflozin and saxagliptin in combined tablet dosage form was developed and validated using RP-HPLC.

References

14

Practical HPLC Method Development

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Goodman and Gilman's The Pharmacological Basis of Therapeutics

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Discovery and Preclinical Profile of Saxagliptin (BMS-477118):  A Highly Potent, Long-Acting, Orally Active Dipeptidyl Peptidase IV Inhibitor for the Treatment of Type 2 Diabetes

David J. Augeri, Jeffrey A. Robl, David A. Betebenner et al. · Journal of Medicinal Chemistry · 2005 · 617 citations · Full text

Practical HPLC method development

Lloyd R. Snyder, Joseph L. Glajch, Joseph J. Kirkland et al. · Analytica Chimica Acta · 1991 · 245 citations

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Development and Validation of Stability Indicating RP-HPLC Method for Empagliflozin

Sushil D. Patil, Sunil V. Amurutkar, Chandrashekhar D. Upasani · Asian Journal of Pharmaceutical Analysis · 2016 · 48 citations · Full text