Journal of Flow Chemistry · 2017 · 89 citations · 43 references
PharmacyChemical EngineeringPharmaceuticsIndustrial ChemistryPharmaceutical ManufacturingPharmaceutical TechnologyChemical Process DesignContinuous Flow ManufacturingContinuous ManufacturingDrug FormulationDrug Substance ManufacturingProcess Flow AnalysisChemical Process DevelopmentContinuous FlowContinuous Flow ProcessingContinuous Pharmaceutical ProcessingContinuous ProcessingContinuous SynthesisFlow ChemistryFlow-based High-throughput Synthesis
Abstract Flow chemistry has become a vibrant area for research over the past decade. This perspective is intended to capture insights on how these advances have and will continue to impact the development and commercialization of active pharmaceutical ingredients. A series of chemistry examples from a number of pharmaceutical companies will highlight the influence of flow chemistry on this industry.
43
Prediction of Organic Reaction Outcomes Using Machine Learning
Connor W. Coley, Regina Barzilay, Tommi Jaakkola et al. · ACS Central Science · 2017 · 823 citations · Full text
Salvatore Mascia, Patrick L. Heider, Haitao Zhang et al. · Angewandte Chemie International Edition · 2013 · 600 citations · Full text