Thomas O’Connor

Modernizing Pharmaceutical Manufacturing: from Batch to Continuous Production

Sau L. Lee, Thomas O’Connor, Xiaochuan Yang et al. · Journal of Pharmaceutical Innovation · 2015 · 832 citations · Full text

Pharmaceutical Formulation, Industrial Design, Pharmaceutical Supply Chain +5

Design and Commercialization of an End-to-End Continuous Pharmaceutical Production Process: A Pilot Plant Case Study

Christopher J. Testa, Chuntian Hu, Khrystyna Shvedova et al. · Organic Process Research & Development · 2020 · 63 citations

Quality Control Issues, Smart Manufacturing, Process Development +17

Optimization of critical quality attributes in continuous twin-screw wet granulation via design space validated with pilot scale experimental data

Shaun Galbraith, Brendon Ricart, Courtney Stanton et al. · International Journal of Pharmaceutics · 2017 · 59 citations · Full text

Geotechnical Engineering, Engineering, Mechanical Behavior +8

Risk Considerations on Developing a Continuous Crystallization System for Carbamazepine

Xiaochuan Yang, David Acevedo, Adil Mohammad et al. · Organic Process Research & Development · 2017 · 56 citations

Engineering, Continuous Crystallization System, Medicinal Chemistry +17

Quality risk assessment and mitigation of pharmaceutical continuous manufacturing using flowsheet modeling approach

Geng Tian, Abdollah Koolivand, Nilou Arden et al. · Computers & Chemical Engineering · 2019 · 51 citations · Full text

Engineering, Quality Risk Assessment, Industrial Engineering +13