Concepedia

Age-Dependent Effects of apoE Reduction Using Antisense Oligonucleotides in a Model of β-amyloidosis

Tien‐Phat V. Huynh, Fan Liao, Caroline Massad Francis, Grace O. Robinson, Javier Remolina Serrano, Hong Jiang, Joseph Roh, Mary Beth Finn, Patrick M. Sullivan, Thomas J. Esparza,

Neuron · 2017 · 218 citations · 30 references

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30

Apolipoprotein E: high-avidity binding to beta-amyloid and increased frequency of type 4 allele in late-onset familial Alzheimer disease.

Warren J. Strittmatter, Ann M. Saunders, D. E. Schmechel et al. · Proceedings of the National Academy of Sciences · 1993 · 4.3K citations · Full text

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Human apoE Isoforms Differentially Regulate Brain Amyloid-β Peptide Clearance

Joseph M. Castellano, Jungsu Kim, Floy R. Stewart et al. · Science Translational Medicine · 2011 · 1.2K citations

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Apolipoprotein E immunoreactivity in cerebral amyloid deposits and neurofibrillary tangles in Alzheimer's disease and kuru plaque amyloid in Creutzfeldt-Jakob disease

Yoshio Namba, Masanori Tomonaga, Hiroshi Kawasaki et al. · Brain Research · 1991 · 1.2K citations

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Aβ42‐driven cerebral amyloidosis in transgenic mice reveals early and robust pathology

Rebecca Radde, Tristan Bolmont, Stephan A. Kaeser et al. · EMBO Reports · 2006 · 1K citations · Full text

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Apolipoprotein E isoform-dependent amyloid deposition and neuritic degeneration in a mouse model of Alzheimer's disease

David M. Holtzman, Kelly R. Bales, Tanya Tenkova et al. · Proceedings of the National Academy of Sciences · 2000 · 943 citations

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