Concepedia

Luminescent cyclometallated platinum(<scp>ii</scp>) complexes: highly promising EGFR/DNA probes and dual-targeting anticancer agents

Yang Zhang, Qun Luo, Wei Zheng, Zhaoying Wang, Yu Lin, Erlong Zhang, Shuang Lü, Junfeng Xiang, Yao Zhao, Fuyi Wang

Inorganic Chemistry Frontiers · 2017 · 51 citations · 58 references

DOI

Concepts

Abstract

Cyclometallated platinum complexes bearing 4-anilinoquinazolines exhibit high potential as luminescent probes for EGFR/DNA in living cells and dual-targeting anticancer agents.

References

58

New Substructure Filters for Removal of Pan Assay Interference Compounds (PAINS) from Screening Libraries and for Their Exclusion in Bioassays

Jonathan B. Baell, Georgina A. Holloway · Journal of Medicinal Chemistry · 2010 · 3.9K citations

, , +14

Direct evidence for a G-quadruplex in a promoter region and its targeting with a small molecule to repress c- <i>MYC</i> transcription

Adam Siddiqui-Jain, Cory L. Grand, David J. Bearss et al. · Proceedings of the National Academy of Sciences · 2002 · 2.2K citations

, , +17

Structure of a B-DNA dodecamer: conformation and dynamics.

Horace R. Drew, Richard M. Wing, T. Takano et al. · Proceedings of the National Academy of Sciences · 1981 · 1.5K citations · Full text

, , +4

Structure of the Epidermal Growth Factor Receptor Kinase Domain Alone and in Complex with a 4-Anilinoquinazoline Inhibitor

Jennifer L. Stamos, Mark X. Sliwkowski, Charles Eigenbrot · Journal of Biological Chemistry · 2002 · 1.5K citations · Full text

, , +16

Light-Emitting Tridentate Cyclometalated Platinum(II) Complexes Containing σ-Alkynyl Auxiliaries:  Tuning of Photo- and Electrophosphorescence

Wei Lu, Baoxiu Mi, Michael C. W. Chan et al. · Journal of the American Chemical Society · 2004 · 613 citations

, , +17