Concepedia

Vanadium pentoxide increased PTEN and decreased SHP1 expression in NK-92MI cells, affecting PI3K-AKT-mTOR and Ras-MAPK pathways

Francisco Gallardo-Vera, Miguel Tapia‐Rodríguez, Daniel Díaz, Teresa I. Fortoul van der Goes, Luis F. Montaño, Erika P. Rendón‐Huerta

Journal of Immunotoxicology · 2017 · 24 citations · 38 references

DOIFull text

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Concepts

Abstract

on NK cells that was due in part to dysregulation of signaling pathways mediated by IL-2 via increased PTEN and decreased SHP1 expression. These results can help to explain some of the known deleterious effects of this particular form of vanadium on innate immune responses

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