Concepedia

Immune System Toxicity

Immune System Toxicity is a type of toxicological effect in which exposure to a chemical, physical, or biological agent produces adverse functional and/or structural alterations in components of the immune system, resulting in impaired immune competence or dysregulated immune responses (including immunosuppression, inappropriate stimulation, hypersensitivity, or autoimmunity).

1.3K

Publications

54.8K

Citations

5.3K

Authors

1.4K

Institutions

Publications per year

2017–2026

206

Parents

Children

Publications

1.3K

Passive Immunization Against Cachectin/Tumor Necrosis Factor Protects Mice from Lethal Effect of Endotoxin

Bruce Beutler, Ian W. Milsark, Anthony Cerami · Science · 1985 · 2.4K citations

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IUPAC glossary of terms used in immunotoxicology (IUPAC Recommendations 2012)

Douglas M. Templeton, Michael Schwenk, Reinhild Klein et al. · Pure and Applied Chemistry · 2012 · 692 citations · Full text

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In vivo administration of purified human interleukin 2. II. Half life, immunologic effects, and expansion of peripheral lymphoid cells in vivo with recombinant IL 2.

Michael T. Lotze, Yvedt L. Matory, Stephen E. Ettinghausen et al. · The Journal of Immunology · 1985 · 614 citations

, , +9

Comprehensive toxicity and immunogenicity studies reveal minimal effects in mice following sustained dosing of extracellular vesicles derived from HEK293T cells

Xiaohua Zhu, Mohamed Badawi, Steven Pomeroy et al. · Journal of Extracellular Vesicles · 2017 · 579 citations · Full text

, , +15

Endotoxin-induced uveitis in rats as a model for human disease

James T. Rosenbaum, H O McDevitt, R. B. Guss et al. · Nature · 1980 · 556 citations

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1–5 of 1.3K

Authors

5.3K

  1. DR
    Dori R. Germolec

    National Institute of Environmental Health Sciences, United States

    23 publications · 983 citations

    15

    h-index

  2. KL
    Kimber L. White

    Virginia Commonwealth University, United States

    19 publications · 478 citations

    14

    h-index

  3. JG
    Joseph G. Vos

    National Institute for Public Health and the Environment, Netherlands

    15 publications · 926 citations

    13

    h-index

  4. MP
    Michael P. Holsapple

    Virginia Commonwealth University Medical Center, United States

    13 publications · 381 citations

    13

    h-index

  5. AE
    Albert E. Munson

    Virginia Commonwealth University Medical Center, United States

    14 publications · 347 citations

    12

    h-index

1–5 of 5.3K

Institutions

1.4K

  1. National Institute for Public Health and the Environment

    De Bilt, The Netherlands

    23 h-index

    91 publications

    4.5K citations

  2. National Institute of Environmental Health Sciences

    Durham, United States

    22 h-index

    98 publications

    3.7K citations

  3. National Institutes of Health

    Bethesda, United States

    21 h-index

    78 publications

    8.4K citations

  4. Research Triangle Park Foundation

    Durham, United States

    19 h-index

    67 publications

    2.5K citations

  5. Virginia Commonwealth University Medical Center

    Richmond, United States

    17 h-index

    75 publications

    2.1K citations

  6. Utrecht University

    Utrecht, The Netherlands

    16 h-index

    43 publications

    2.1K citations

  7. Environmental Protection Agency

    Washington, United States

    15 h-index

    47 publications

    1.9K citations

  8. University of Milan

    Milan, Italy

    13 h-index

    50 publications

    3.4K citations

1–8 of 1.4K

Venues

  1. PubMed

    Repository · 124 publications · 4K citations

    36

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  2. Toxicological Sciences

    45 publications · 2.2K citations

    30

    h-index

  3. Toxicology and Applied Pharmacology

    TAAP · 42 publications · 2.9K citations

    30

    h-index

  4. Toxicology

    47 publications · 1.9K citations

    28

    h-index

  5. Journal of Immunotoxicology

    47 publications · 1.3K citations

    24

    h-index

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