ITK and RLK Inhibitor PRN694 Improves Skin Disease in Two Mouse Models of Psoriasis

Imiquimod-Induced Psoriasis-Like Skin Inflammation in Mice Is Mediated via the IL-23/IL-17 Axis

Leslie van der Fits, Sabine Mourits, Jane S.A. Voerman et al. · The Journal of Immunology · 2009 · 2.1K citations · Full text

Medicine, Dermatology, Immunology +17

Genome-wide scan reveals association of psoriasis with IL-23 and NF-κB pathways

Rajan P. Nair, Kristina Callis Duffin, Cynthia Helms et al. · Nature Genetics · 2009 · 1.4K citations · Full text

Life Sciences, Genetics, Immunology +14

Psoriasis Vulgaris Lesions Contain Discrete Populations of Th1 and Th17 T Cells

Michelle A. Lowes, Toyoko Kikuchi, Judilyn Fuentes‐Duculan et al. · Journal of Investigative Dermatology · 2008 · 1.1K citations · Full text

Life Sciences, Dermatology, Immunology +12

Pivotal Role of Dermal IL-17-Producing γδ T Cells in Skin Inflammation

Yihua Cai, Xiaoyan Shen, Chuanlin Ding et al. · Immunity · 2011 · 1K citations · Full text

Medicine, Dermatology, Immunology +16

Stat3 links activated keratinocytes and immunocytes required for development of psoriasis in a novel transgenic mouse model

Shigetoshi Sano, Keith Syson Chan, Steve Carbajal et al. · Nature Medicine · 2004 · 747 citations

Medicine, Cell Biology, Dermatology +14